Synthetic chemicals for research, scientific purposes.
Articles on pharmaceuticals, synthetic drugs
Triftazine is a neuroleptic containing trifluoperazine hydrochloride. It is one of the most active antipsychotics, affects certain brain cells, eliminates mental disorders well, accompanied by hallucinations, delusions, and has a pronounced antiemetic effect. With prolonged use, addiction develops. After withdrawal, various neurological and psychopathological symptoms are possible. What was the drug created for? Trifluoperazine belongsRead More
The FDA has approved the use of the first innovative non-opioid analgesic in 20 years, which blocks pain signals without affecting the central nervous system. The drug developed by Vertex has shown high efficacy in clinical trials and may become an alternative to opioids, which tens of thousands of people become addicted to every year.Read More
Pharmacodynamic classification of psychostimulants Indirect adrenomimetics increase the release of endogenous catecholamines from presynaptic depots, inhibit the reuptake of mediators and increase their concentration in the synaptic cleft. Phenylalkylamine derivatives Phenamine (amphetamine, benzedrine) is the most active psychostimulant. It enhances the activity of the adrenergic system (activation of glycogenolysis and lipolysis), promotes the mobilization, deliveryRead More
This group includes narcotic analgesics (from Greek algos — pain and an — without), which have a pronounced ability to weaken or eliminate the feeling of pain. Substances with different chemical structures exhibit analgesic activity, and it is realized by various mechanisms. Modern analgesics are divided into two main groups: narcotic and non-narcotic. Narcotic analgesics,Read More
Phenylpiracetam, also known as Phenotropil or Nootropil, Actitropil, and Carphedon , is a popular drug from the group of nootropics. This pharmacological component, based on the structure of piracetam, is widely used to improve cognitive functions and increase energy levels in humans. However, in addition to the positive effects, this drug can cause some sideRead More
Opioids are medications. Pharmacology of opioid analgesics Given the centuries-old history of the use of opium and its alkaloids, it was only in 1973 that the presence of membrane receptors called “opioids” in the central nervous system was experimentally proven. A little later, it was possible to detect in the body the first substance stimulatingRead More
Dissociative drugs (also called “dissociative anesthetics”) are a type of psychedelics that cause distorted sensory perception and isolation from the environment. These substances greatly distort the perception of vision and sound. People who use dissociatives are in a dream-like state. Everything that happens around you seems unreal and blurry, there is confusion, detachment from emotions,Read More
Anticholinergic, or cholinolytic, agents are substances that weaken, prevent or stop the interaction of acetylcholine with cholinergic receptors. By blocking cholinergic receptors, they act in the opposite way to acetylcholine. In accordance with the division of cholinergic receptors into m- and n-cholinergic receptors, cholinolytic substances are also divided into substances with a predominant m- orRead More
Synthetic cathinones are a subgroup of NSAIDs that can be considered as structural derivatives of cathinone, which is the main active ingredient of the cat plant. Thus, synthetic cathinones are β–ketophenethylamines, and methcathinone, for example, is also known as β-ketoamphetamine and has a stimulating effect similar to that of amphetamine. A number of synthetic cathinonesRead More
History Α-Pyrrolidinopentiophenone was developed by the German pharmaceutical company Boehringer Ingelheim in the 1960s as a central nervous system stimulant.However, its illegal use as a recreational psychostimulant began about 10 years ago in the USA, Europe (Norway, Denmark, Finland, Iceland, Sweden) and Japan. The substance is often sold under the guise of “bath salts”. InRead More
